Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity connected to bortezomib, a proteasome inhibitor Utilized in the cure of a number of myeloma. Its synthesis or examine is vital for making sure the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the procedure of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A important compound during the synthesis of imatinib, a drug that targets distinct varieties of most cancers, like chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is vital for optimizing the generation system and making certain high purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to treat breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Utilized in the procedure of breast cancer. Several intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): 5'-dibenzoate This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers like ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal most cancers and modest mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is linked to the synthesis of adamantane derivatives, that have various programs, which includes antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for form two diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of varied gluconic acid derivatives, which might be Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin CAS 702-82-9 Intermediate 2: A precursor during the synthesis of canagliflozin, a medication utilized to manage type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).